Applications of Hantzsch Esters in Organocatalytic Enantioselective Synthesis

Hantzsch esters (1,4-dihydropyridine dicarboxylates) have become, in this century, very versatile reagents for enantioselective organic transformations. They can act as hydride transfer agents to reduce, regioselectively, a variety of multiple bonds, e.g., C=C and C=N, under mild reaction conditions. are excellent the dearomatization heteroaromatic substances, participate readily cascade processes. In last few years, they also become useful photoredox reactions. sacrificial electron hydrogen donors when 4-alkyl or 4-acyl-substituted, alkyl acyl radical agents. These reactions may take place presence absence photocatalyst. This review surveys literature published area five years.